Effect of Alanyl-glutamine on Aged Patients with Severe Pneumonia / 药物流行病学杂志

ABSTRACT

Objective:To study the effect of alanyl-glutamine(Ala-Gln) on aged patients with severe pneumonia. Methods:The hospital acquired 56 cases of patients with severe pneumonia,who were randomized in two groupsAla-Gln group in 30 cases and controlled group in 26 cases Both groups were cared with anti-infection,nutrition support and symptomatic treatment,during which Ala-Gln group was supplemented with 10g alanyl-glutamine amid 250ml amino acid intravenous drip in 14 days,two times each.Before and after the treatment,both groups were monitored over their intestinal functions and measured over their Alb,IgG,total lymphocytes count,C-reactive protein,nitrogen balance,blood routine,liver and kidney function examinations.Result:There were statistical differences between the groups involving intestinal function monitoring(P