Refractory Hypertension and Isosexual Pseudoprecocious Puberty Associated with Renin-Secreting Ovarian Steroid Cell Tumor in a Girl
Journal of Korean Medical Science
;
: 836-838, 2011.
Article
in English
| WPRIM
| ID: wpr-58113
ABSTRACT
Steroid cell tumor, not otherwise specified (NOS), are rare ovarian tumor, in addition, it is more rare in children. The majority of these tumors produce several steroid hormones, particularly testosterone. Estrogen also secreted by steroid cell tumor, NOS, but it is uncommon. Furthermore, hypertension is an infrequent sign in steroid cell tumor, NOS. An 8.5-yr-old girl with hypertension and frequent vaginal spotting visited at our clinic. On laboratory evaluation, secondary hypertension due to an elevated plasma renin level and isosexual pseudoprecocious puberty was diagnosed. Right solid ovarian mass was detected in radiologic tests. She underwent a right ooporectomy and it revealed renin and progesterone receptor positive steroid cell tumor, NOS. After operation, her blood pressure returned to normal level and vaginal bleeding disappeared. Even though this case is very rare, when hypertension coincides with virilization or feminization, a renin-secreting ovarian steroid cell tumor, NOS, should be considered.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ovarian Neoplasms
/
Puberty, Precocious
/
Steroids
/
Receptors, Progesterone
/
Tomography, X-Ray Computed
/
Renin
/
Sex Cord-Gonadal Stromal Tumors
/
Receptors, Cell Surface
/
Vacuolar Proton-Translocating ATPases
/
Hypertension
Limits:
Child
/
Female
/
Humans
Language:
English
Journal:
Journal of Korean Medical Science
Year:
2011
Type:
Article
Similar
MEDLINE
...
LILACS
LIS