Effects of polycylic aromatic hydrocarbons on plasma monoamine neurotransmitters / 重庆医科大学学报
Journal of Chongqing Medical University
;
(12)2003.
Article
in Chinese
| WPRIM
| ID: wpr-581145
ABSTRACT
Objective:
To explore the effect of polycylic aromatic hydrocarbons (PAHs)on plasma monoamine neurotransmitters.Methods:
80 healthy adult male coke oven workers were selected from a coke plant of a state-owned steel enterprise,80 controls were selected from the oxygen factory. Concentration of benzo[a]pyrene(B[a])P in the working environment was monitored by high performance liquid chromatography(HPLC)with fluorescence detector. The level of urinary 1-hydroxypyrene(1-OHP)was determ ined by HPLC with fluorescence detector.The plasma noradrenaline(NE),adrenaline(AD),dopamine(DA)and serotonin(5-HT)levels were measured by high performance liquid chromatography (HPLC) with electrochemical detection.Results:
In the working environment of B[a]P, concentration in coke oven workers were significantly higher than controls (P
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Chongqing Medical University
Year:
2003
Type:
Article
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