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EXPERIMENTAL STUDIES ON ANTITHROMBOSIS OF EICOSAPENTAENOIC ACID / 中国海洋药物
Chinese Journal of Marine Drugs ; (6)1994.
Article in Chinese | WPRIM | ID: wpr-581673
ABSTRACT
The effects of eicosapentaenoic acid (EPA) on experimental thrombosis and its mechanism were studied. The results showed that eicosapentaenoic acid had a significant antithrombolic effect both in vivo and in vitro . EPA also had a fibrinolytic activity and can shorten euglobulin lysis time. Our studies also showed that EPA can inhibit platelet aggregation in rats. The plasma concentration of 6-keto-PGF1a and TXB2 was measured by radioimmunoassay. The results showed that EPA can reduce the contents of TXB2 and raise 6-keto-PGF1a/TXB2 ratio.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Marine Drugs Year: 1994 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Marine Drugs Year: 1994 Type: Article