A study on the relationship between TNF-? and diabetic retinopathy in rat / 中国糖尿病杂志
Chinese Journal of Diabetes
;
(12)1994.
Article
in Chinese
| WPRIM
| ID: wpr-582117
ABSTRACT
Objective To study the relationship between serum level of TNF-? and morphologic changes as well as related factors in 3 and 6 months of diabetic retinopathy rats. Methods This research successfully duplicated a model of insulin dependent diabetes mellitus in rats and carried out morphologic observation of retina of diabetic rat when the disease lasted for 3 and 6 months. The serum level of TNF-? by ELISA together with related factors, such as blood glucose (BG)by oxidase method、glucosylated hemoglobin (GHbAlc) 、serum insulin (Ins) and c-peptide (C-P) by RIA were studied. Results In same duration,the levels of TNF-?、BG、GHbAlC in model groups were significantly higher than therapy groups (P
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Chinese Journal of Diabetes
Year:
1994
Type:
Article
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