A study of the association between polymorphism of endothelial nitric oxide synthase gene and diabetic nephropathy / 中国糖尿病杂志
Chinese Journal of Diabetes
;
(12)1994.
Article
in Chinese
| WPRIM
| ID: wpr-582448
ABSTRACT
Objective To investigate the association between a 894 G→T mutation at exon 7 of eNOS gene and diabetic nephropathy in type 2 diabetes mellitus of northern chinese Methods A case control study for 228 chinese subjects (including 143 type 2 diabetes mellitus with or without nephropathy and 85 normal control)was performed The number of the 894 G→T mutation alleles were determined by polymerase chain reaction and restriction fragment length polymorphism(PCR RFLP) method combined by DNA sequencing Results The frequency of the T allele and TG genotype at exon 7 were significantly higher in DN+ group than in DN group and control subjects(P
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Observational study
/
Risk factors
Language:
Chinese
Journal:
Chinese Journal of Diabetes
Year:
1994
Type:
Article
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