Effect of 0.05% Cyclosporine A on the Ocular Surface after Photorefractive Keratectomy
Journal of the Korean Ophthalmological Society
;
: 710-717, 2016.
Article
in Korean
| WPRIM
| ID: wpr-58330
ABSTRACT
PURPOSE:
To evaluate the effect of 0.05% cyclosporine A on the ocular surface after photorefractive keratectomy (PRK).METHODS:
This retrospective study included 50 patients who underwent PRK. Patients were divided into two groups 25 patients in group I were treated with topical 0.05% cyclosporine A with conventional medication, and 25 patients in group II were treated with conventional medication. Visual acuity (VA), tear break-up time (BUT), fluorescein staining score (F-stain), Schirmer I test, and ocular surface disease index (OSDI) were evaluated before surgery and 2 weeks, 1 month, 2 months, and 3 months after surgery.RESULTS:
F-stain was significantly lower in group I than in group II at 2 weeks and 1 month (p < 0.05). There was no significant difference in uncorrected VA, BUT, Schirmer I test, or OSDI between the groups. However, group I showed a more effective pattern in dry eye.CONCLUSIONS:
Combination treatment with 0.05% cyclosporine A was helpful for early ocular surface stability in patients with dry eye after PRK.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Tears
/
Visual Acuity
/
Retrospective Studies
/
Cyclosporine
/
Photorefractive Keratectomy
/
Fluorescein
/
Refractive Surgical Procedures
Type of study:
Observational study
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Ophthalmological Society
Year:
2016
Type:
Article
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