Association of TNF-? gene polymorphism with Graves′ ophthalmopathy / 医学研究生学报
Journal of Medical Postgraduates
;
(12)2004.
Article
in Chinese
| WPRIM
| ID: wpr-584458
ABSTRACT
Objective:
To investigate the association of tumour necrosis factor- ? (TNFs-?) gene polymorphism with Graves ophthalmopathy (GO)Chinese in Shandong .Methods:
Allele and genotype frequencies were determined by polymerase chain reaction with sequence specific primers(PCR-SSP).Results:
Allele and genotype frequencies of TNF-? +488、-308 were not different significantly between Graves′ disease(GD) and control, or GD subgroups with and without GO. There were also no significant differences between GO subgroups with different severity.Conclusion:
There are no associations of TNF-? +488、–308 polymorphisms with GO susceptibility in Shandong Chinese.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Medical Postgraduates
Year:
2004
Type:
Article
Similar
MEDLINE
...
LILACS
LIS