Studies on uticaris and quincke edema due to allergy of medications

ABSTRACT

Studies on uticaris and quincke edema due to allergy of medications at the ward of Allergology and clinical immunology of Bach mai hospital (1991-2000). Result showed that almost medications are used in medical clinic can cause allergic reactions. There were 393 kinds of medication that caused allergic reaction on 375 patients. In 23 different groups of medication. Antibiotics were main cause (67.2%) of allergic reactions, Beta-lactam class is 60.6% in the antibiotic group. besides urticaria and Quincke edema, there are many other clinical symptoms of allery from 375 in-patients fever, erythema, dermatitis, dispnea. Allergic reactions were happened early (before 24 hours). Elevated ESR, white blood cell are main changes of teast. It takes short time to treat allergic patients (7.9 to 5.6 days). Solution of Methyl-Prednisolon, Dimedrol, Ascorbic acid and glucose 5% are common medications to treat this patients. No death occurred in patients of urticaria and Qincke edema during study periof.