A Controlled Clinical Trial of Citalopram and Citalopram Combined with Psychotherapy in the Treatment of Postpartum Depression / 中国心理卫生杂志

ABSTRACT

Objective:To compare the efficacy of citalopram alone and citalopram combined with psychotherapy in patients with postpartum depression. Methods:Fifty-eight women who met CCMD-3 criteria for postpartum depression were randomly assigned to 2 groups. Group A was treated with citalopram 20mg daily alone, group B with citalopram 20mg daily combined with psychotherapy, both for six weeks. Hamilton rating scale (HAMD) was evaluated at baseline and after 1, 2, 4 and 6 weeks of treatment. Results:HAMD scores were decreased with statistical significance since week 1 in group A and since week 2 in group B. At different time points the HAMD scores in group A were lower than those in group B with statistically significant difference. Conclusion: Citalopram combined with psychotherapy was more effective than citalopram alone in the treatment of postpartum depression.