Antimicrobial Activity in vitro of ?-Lactams and ?-Lactamase Inhibitors Against Bacteria of Hospital Acquired Infection / 中华医院感染学杂志
Chinese Journal of Nosocomiology
;
(24)1994.
Article
in Chinese
| WPRIM
| ID: wpr-585710
ABSTRACT
OBJECTIVE Tostuty the antimicrobial activity in vitro of 13 ?-lactams and the combinations of (?-lactams) and(?-lactamase) inhibitors against 84 isolates of Klebsiella pneumoniae and Escherichia coli.METHODS MICs were determined by agar dilution method.RESULTS The antimicrobial activity of combinations of ?-lactams and(?-lactamase) inhibitors was the strongest,and the activity of ?-lactams and qinolones were inferior,and ?-lactams were invalid.CONCLUSIONS In the antimicrobial spectrum and antimicrobial activity the combinations of ?-lactam and ?-lactamase inhibitors were stronger than that of ?-lactam.The use of combinations of ?-lactam and ?-lactamase(inhibitors) may increase the clinical cure rate,and delay the occurrence of resistance.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Nosocomiology
Year:
1994
Type:
Article
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