Development of orthopaedic biomechanics / 中华创伤骨科杂志

ABSTRACT

Heartening advances continue to be made in numerous research areas of orthopedic biomechanics. Recently, orthopedic research has been greatly expanded, ranging from the cellular level to the whole body level. One of the most important research focuses is a probe into the relationship between biology and mechanics. Emerging information about genetic basis of bone and cartilage pathology is used to provide insight into the fundamental mechanism of common conditions, such as osteoporosis and degenerative arthritis. Other ardent areas of investigation include tissue engineering, biomaterials, tendon healing, and biomechanical properties of tissue at the microscopic level. Interdisciplinary research currently affords a partly unrealized potential to relate the mechanical environment to biological responsiveness. New approaches include iterative computational modeling allowing model parameters at the microscopic level, micro- mechanics, and relatively long- term in vivo manipulation of the mechanical environment. The field of orthopedic biomechanics is widely researched and has led to improved surgical procedures in such areas as bone grafting, joint replacement, and limb supports.