Common Gram-negative Bacilli Infection and Antibiotic Resistance Analysis in Lower Respiratory Tract Disease among Aged People in Chengdu Region / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To monitor drug resistance of the 5 kinds of Gram negative bacilli isolated from the old patients with lower respiratory tracts infection in Chengdu region. METHODS From Jan 2002 to Jun 2004,we collected the sputum samples of the old patients who were diagnosed lower respiratory tract infection with Gram negative bacilli,which were analyzed with automatic VITEK32 and 532 strains of common Gram negative bacilli were identified. RESULTS The most common 5 kinds of Gram negative bacilli,which were cultured among old patients in Chengdu region with lower respiratory tracts infection,were Escherichia coli(27.44%),Klebsiella pneumoniae(20.49%),Pseudomonas aeruginosa(18.23%),Acinetobacter baumannii(17.67%),and Enterobacter cloacae(16.17%).For above bacteria,the ratio of the resistance to amoxicillin/clavulanic acid,ampicillin,cefazolin,compound sulfamethoxazole was over 40%.And the isolating rate of ESBLs produced by (E.coli) and K.pneumoniae was 20.78%. CONCLUSIONS Monitoring the common bacteria and ESBLs-producing bacteria precisely can provide therapy,guide to early cure and control lower respiratory tracts infection of aged patients effectively.