Antimicrobial Activities of Traditional Chinese Materia Medica Extracts / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To discuss the antimicrobial activity of extracts from 10 kinds of traditional Chinese materia(medica)(TCMM)in vitro.METHODS Extracts from 10 kinds of TCMM were prepared,and subjected to(bacteriostatic) tests in vitro by test tube continuously dilution in order to observe their minimal inhibitory(concentration)(MIC),to Staphylococcus(aureus),Escherichia coli,Pseudomonas aeruginosa and Candida albicans.RESULTS Among the 10 kinds of TCMM extracts,which did have antimicrobial activity against S.aureus,E.coli,P.aeruginosa and C.albicans in(different) degree;among them,the antimicrobial(activit)y of the extracts of Radix Paeoniae Rubra,Punica granatum,Schisandra chinensis and Coptis chinensis to resistant bacteria was the highest,the extracts of(Radix) Paeoniae Rubra showed strong inhibitory activities to the above 4 bacteria,especially to the resistant(organisms) with the MIC at 7.8,1.95,1.95 and 7.8mg/ml,(respectively).CONCLUSIONS The extracts of Radix Paeoniae Rubra,P.granatum,S.chinensis and C.chinensis have broad spectrum of antimicrobial activity to(resistant) bacteria.