Study on antiviral effect of indole-2,3-dine / 中国海洋药物
Chinese Journal of Marine Drugs
;
(6)1994.
Article
in Chinese
| WPRIM
| ID: wpr-587248
ABSTRACT
Objective To investigate antiviral and immunoregulation effects of indole-2,3-dine(ISA).Methods The BHK-21 cell model infected with Sendai virus was established and the antiviral effect of ISA was observed by cytopathic effect(CPE) method;its effect on immunological function was observed by hemagglutination inhibition test using Sendai virus infected mice model.Results ISA showed cytotoxicity when the concentration was above(0.313)mg?mL~(-1),while ISA showed a dose-dependent antiviral effect without cytotoxicity when the concentration was among 0.156~0.039mg?mL~(-1).ISA at higher dose(2%) could accelerate the production of hemagglutination inhibition antibody in hemagglutination test(P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Marine Drugs
Year:
1994
Type:
Article
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