Associations between serum vitamin D levels and precocious puberty in girls
Annals of Pediatric Endocrinology & Metabolism
;
: 91-95, 2014.
Article
in English
| WPRIM
| ID: wpr-58752
ABSTRACT
PURPOSE:
Vitamin D deficiency has been linked to chronic diseases, such as diabetes mellitus, obesity and autoimmune disease. However, data on the vitamin D status and its association with precocious puberty in girls are limited. We aimed to investigate the association between serum 25-hydroxyvitamin D (25OHD) and precocious puberty in girls.METHODS:
A total of 60 girls with central precocious puberty (CPP) and 30 control girls were enrolled. Anthropometric measurement and serum level of 25OHD were estimated for all subjects.RESULTS:
There was a significant difference in the mean serum 25OHD concentration between the precocious puberty group and the control group (17.1+/-4.5 ng/mL vs. 21.2+/-5.0 ng/mL, P30 ng/mL). Vitamin D deficient girls had a significantly higher odds ratio (OR, 3.05; 95% CI, 1.22-7.57, P=0.021).CONCLUSION:
These results showed that vitamin D levels may be associated with precocious puberty. Further studies are required to establish the potential effect of vitamin D status on puberty.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Puberty, Precocious
/
Autoimmune Diseases
/
Vitamin D
/
Vitamin D Deficiency
/
Odds Ratio
/
Chronic Disease
/
Puberty
/
Diabetes Mellitus
/
Obesity
Type of study:
Etiology study
Limits:
Adolescent
/
Female
/
Humans
Language:
English
Journal:
Annals of Pediatric Endocrinology & Metabolism
Year:
2014
Type:
Article
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