Eph receptor tyrosine kinase and its relation to cancer / 医学研究生学报
Journal of Medical Postgraduates
;
(12)2003.
Article
in Chinese
| WPRIM
| ID: wpr-587586
ABSTRACT
Eph,the largest subfamily of tyrosine kinase receptor, could be divided into two groups,EphA and EphB.Ephs play a role in the embryonic development and differentiation of the nervous and vascular systems. In recent years,a large number of ephrins and Ephs had been found to be overexpressed in numerous human tumors,and have relation to development and prognosis of cancers.Down-regulated of EphA3 and EphA7 in cancers,was attributed to the hypermethylaiton of CpG island in promoter region.
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Medical Postgraduates
Year:
2003
Type:
Article
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