Association between Dopamine Receptor D4 Polymorphisms and Novelty Seeking Personality Trait in a Korean Population / 신경정신의학
Journal of Korean Neuropsychiatric Association
;
: 630-637, 2002.
Article
in Korean
| WPRIM
| ID: wpr-58869
ABSTRACT
OBJECTIVES:
We investigated the relationship of personality traits with dopamine D4 receptor(DRD4) exon III polymorphism in a Korean population.METHODS:
We analysed DRD4 exon III 48-bp repeats polymorphism in 173 Korean healthy female adolescents(age=13.88+/-0.29 years) who also completed Temperament and Character Inventory(TCI).RESULTS:
Novelty seeking score of the TCI was significantly higher in the subjects with DRD4 long alleles(>or=5 repeats) compared with the subjects without these(t=2.11, p=0.037).CONCLUSION:
The present study supports the previous reports that long repeats of the DRD4-exon III polymorphism are related with Novelty Seeking personality.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Temperament
/
Dopamine
/
Exons
/
Receptors, Dopamine
Limits:
Female
/
Humans
Language:
Korean
Journal:
Journal of Korean Neuropsychiatric Association
Year:
2002
Type:
Article
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