Effect of Ginsenoside Rg1 on the expression of neuron specific enolase following focal cerebral ischemia in rats and its significance / 临床神经病学杂志
Journal of Clinical Neurology
;
(6)1988.
Article
in Chinese
| WPRIM
| ID: wpr-588907
ABSTRACT
Objective To investigate the effect and significance of Ginsenoside Rg1 on the expression of neuron specific enolase (NSE) after focal cerebral ischemia in adult rats.Methods Ginsenoside Rg1 was given intraperitoneally in the rats twice a day at dose of 20 mg/kg for 5 days. Then the models of cerebral ischemia were made by occluding middle cerebral artery using an intraluminal filament method. At 3, 24, 48 and 72 h after focal cerebral ischemia, the neurological deficit score was evaluated and immunohistochemistry technique was used to observe the expressions of NSE. The above parameters were compared to control group and sham operation group.Results Compared with control group,at all the time points the neurological deficit scores were significantly decreased in Ginsenoside Rg1 group (all P
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Journal of Clinical Neurology
Year:
1988
Type:
Article
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