Protective effect of heme oxygenase-1 induced by doxorubicin on hepatic ischemia-reperfusion in rats / 吉林大学学报(医学版)
Journal of Jilin University(Medicine Edition)
;
(6)2006.
Article
in Chinese
| WPRIM
| ID: wpr-589573
ABSTRACT
0.05).The results of Western blotting and immunohistochemical method showed that HO-1 protein expression increased in DOX group and DOX-IR group,and was negative in normal group.More distruction of ultrastructural changes of hepatic cells in IR group was found than in DOX-IR group by transmission electron microscope.Conclusion Doxorubicin pretreatment could protect the liver from ischemia-reperfusion injury,which may be related to HO-1 expression induced by doxorubicin,low dosage of doxorubicin does little harm to rat liver.
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Jilin University(Medicine Edition)
Year:
2006
Type:
Article
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