An experimental study on the treatment of osteoporosis with andriol in male rats / 医学研究生学报

ABSTRACT

Objective:To study the effect of androgen on osteoporosis(Op) in male rats.Methods: Thirty-two 15-week-old male Spague-Dawley rats underwent orchidectomy and then were randomly divided into 3 groups a normal controls,a model and a andriol treated group.Biochemical markers,bone density(BMD) and bone histomorphometry were investigated after 28 weeks.Results: Orchidectomy caused a significantly decreased in the level of testosterone(P