Quantification of Retinal Nerve Fiber Layer Thickness in Different Orientation in Normal Subjects / 中山大学学报(医学科学版)

ABSTRACT

【Objective】To measure RNFL thickness (clock type and mean) and investigate the relationship between RNFL thickness and age,gender,and right or left eye in normal subjects using OCT.【Methods】OCT was used in 183 eyes of 104 normal subjects to measure RNFL thickness with circle scan (scan diameter of 3.46mm) around optic nerve head.【Results】RNFL thickness (μm) measured by OCT in normal eyes according to clock type (1030～、1130～、1230～、130～、230～、330～、430～、530～、630～、730～、830～、930～) were 144±14、141±16、135±12、104±17、78±15、90±18、130±16、147±17、145±13、92±16、80±11、103±10,respectively，and mean of whole circle was (116±5) μm.There was a negative correlation between RNFL thickness in temple-superior (1030～1230),temple- inferior (530～730),mean thickness and age (P=0.005～0.000).There was no significant differences between RNFL thickness of various clock and mean (P=0.356～0.781),gender and right or left eye (P=0.155～0.612).【Conclusion】RNFL thickness was thicker in temple-superior (1030～1230) and temple-inferior (530～730),thinner in nasal (230～) and temple (830～) in normal subjects.The elder of persons,the thinner of RNFL thickness.RNFL thickness was not related to gender and right or left eye.