Two Cases of Elephantiasis Neurofibromatosa Treated with Surgery / 대한피부과학회지

ABSTRACT

Elephantiasis neurofibromatosa is the clinical subtype of neurofibromatosis and this clinically represents as a large, ill-defined, soft mass with soft tissue overgrowth and hairy pigmented patches. Histopathologically, an infiltrating and well-demarcated mass that is not encapsulated and the mass is composed of proliferating spindle-shaped cells can be observed in the dermis and subcutis. Mitotic activities should not exist. We herein report on two cases of elephantiasis neurofibromatosa that were treated with surgery. Both patients had had difficulty in walking due to a huge mass that had been on their left legs for more than 20 years. After surgery, they reported improvement of their ambulation.