Treatment of Acne with Isotretinoin in a Patient with Apert's Syndrome / 대한피부과학회지
Korean Journal of Dermatology
;
: 576-579, 2009.
Article
in Korean
| WPRIM
| ID: wpr-59080
ABSTRACT
Apert's syndrome is a rare autosomal dominant disease that's characterized by craniosynostosis and severe syndactyly of both the hands and feet. It is caused by a mutation of the fibroblast growth factor receptor (FGFR) type-2 gene. The development of widespread acne, involving the face, chest, back and forearms, is a characteristic finding at puberty in Apert's syndrome patients. The acne of Apert's syndrome patients is generally resistant to conventional therapy, including topical agents and/or oral antibiotics, but it shows a good response to isotretinoin. We report here on a case of acne that was successfully treated with isotretinoin in a teenager with Apert's syndrome.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Thorax
/
Isotretinoin
/
Puberty
/
Receptors, Fibroblast Growth Factor
/
Acne Vulgaris
/
Syndactyly
/
Craniosynostoses
/
Foot
/
Forearm
/
Hand
Limits:
Adolescent
/
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2009
Type:
Article
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