Application of CT perfusionimaging in assessing the physiological state of solitary pulmonary nodules / 中国组织工程研究

ABSTRACT

0.05); mean transit time was significantly lower but permeability surface area product higher than benign nodules (P 0.05). ③If the mean transit time ≤ 7 s was selected as cut-off value for malignant lesion, the sensitivity was 68.97%, specificity was 66.67%, accuracy was 68.49%, positive predict value was 88.89%, and negative predict value was 35.71%. When permeability surface area product ≥ 0.20 was selected as the cut-off value for malignant lesion, the sensitivity, specificity, accuracy, positive predict value, and negative predict value were 86.21%, 53.33%, 79.45%, 87.72%, and 50.0%, respectively. CONCLUSION: CT perfusion imaging is a valuable method for assessing the physiological state of solitary pulmonary nodules.