Role of 6-minute walk test in chronic obstructive pulmonary diseases / 中国组织工程研究

ABSTRACT

AIM: The 6-minute walk test (6MWT) has been acknowledged as a simple and feasible study method of evaluating cardiorespiratory function, motor ability and quality of life in all testees. This study was designed to evaluate the value of 6MWT in patients with chronic obstructive pulmonary disease (COPD). METHODS: ①Fifty patients diagnosed with COPD were enrolled from Department of Respiratory Medicine in the Second Clinical Medical College of Jinan University from January 2001 to December 2006, including 34 males and 16 females, with a mean age of (70.1?8.9) years; and 62 patients with other diseases admitted in Department of Respiratory Medicine were taken as controls, including 30 males and 32 females, with a mean age of (66.5?10.1) years. Informed consents were obtained from all testees.②All patients were tested with 6MWT, lung function and MRC dyspnea scale, and the results were conducted for t test, ROC curve analysis, linear correlation analysis and multiple stepwise regression analysis. Pearson correlation coefficient was also calculated. RESULTS: All the testees were involved in the result analysis.①6MWT results: Compared with control group, the degression fraction of blood oxygen saturation was significantly higher and 6-minute walk distance was significantly shorter in the COPD patients (P