Protective effect of prostaglandin E1 on platelet during cardiopulmonary bypass / 临床检验杂志
Chinese Journal of Clinical Laboratory Science
;
(12)2006.
Article
in Chinese
| WPRIM
| ID: wpr-591607
ABSTRACT
Objective To investigate the protective effect of prostaglandin E1 (PGE1) on platelet during cardiopulmonary bypass (CPB).Methods A total of 24 patients undergoing cardiac valve replacement were randomly divided into the experimental group (n=12) and the control group (n=12).The levels of thromboxane B2 (TXB2) and 6-keto-prostaglandin F1?(6-K-PGF1?) in serum were measured at different intervals during and after CPB. The ultrastructure of platelets was also observed by transmission electron microscope.Results The levels of TXB2 and 6-K-PGF1? during CPB were significantly higher than those before CPB in the both groups(P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Clinical Laboratory Science
Year:
2006
Type:
Article
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