Anterior cruciate ligament reconstruction and tendon-bone healing characteristics / 中国组织工程研究

ABSTRACT

Presently,with anterior cruciate ligament reconstruction using autogeneic hamstring tendon graft is generally developed,the influencing factors and promotion methods of tendon-bone healing become a research focus of sports medicine.The influencing factors include the graft fixation,the character of bone,stress stimulation and the matching relation between graft and bone tunnel and so on.The promotion methods include applying growth factors,metalloprotease blocking agent,osteoprotegerin,mesenchyme stem cells,physical methods.Some prospective methods of promoting tendon-bone healing have been found,but these methods are in animal study or involving complex laboratory technique.Thus,these methods require further studies before clinical application.