Distribution and Antimicrobial Resistance of Commonly Encountered Gram-negative Bacilli in Hospital During 2005-2006 / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To investigate the distribution and resistantce of three commonly encountered Gram-negative bacilli in our hospital,and provide doctors with the laboratory evidence of guiding antibiotic therapy.METHODS Bacterial identification and antibiotic susceptibility tests of isolates between Jan 2005 and Dec 2006 were performed by MicroScan WalkAway-40.RESULTS Totally 2024 common Gram-negative bacilli strains were isolated,807 of which were Escherichia coli,737 were Klebsiella pneumoniae,480 were Pseudomonas aeruginosa.The antimicrobial resistant rate of E.coli and K.pneumoniae to imipenem(2.2%) was lower than to the other antibiotics(2.7%).While 14.0% of P.aeruginosa isolates were resistant to imipenem.The antimicrobial resistant rate of all the isolated bacteria to piperacillin/tazobactam and amikacin was low,accounted less than 15%.CONCLUSIONS The resistant rate of three commonly encounted Gram-negative bacilli is increasing year by year.Therefore,monitoring bacterial drug resistance is very important for the rational use of antibiotics and the containment of multi-drug bacteria.