Antimicrobial-resistant Profile in Sulfamethoxazole-trimethoprim Resistant Staphylococcus aureus / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To investigate the antimicrobial-resistant profile of sulfamethoxazole-trimethoprim(SXT) resistant Staphylococcus aureus.METHODS The strains of S.aureus(SAU) were isolated from clinical specimens by routine methods.The identification and susceptibility test of the isolates were determined by Automated Microbiology Analyzer.Disk-diffusion was used for detecting meticillin-resistant S.aureus(MRSA).?2 Test was made to identify the significance of difference.RESULTS 68.0% Of isolates were referred as MRSA.The resistant rates of the isolates of SAU to SXT was 30.8%.The resistant rate of the isolates of MRSA and MSSA to SXT were 27.4% and 38%.60.5% And 71.3% of isolates were referred as MRSA from the SXT-resistant group and MRSA from the SXT-sensitive group.The resistant rate of MRSA from the group of SXT-resistant to tetracycline,levofloxacin and rifampicin were all significantly lower than those of isolates from the SXT-sensitive group(all P