Pathogen Distribution and Drug-resistance Monitoring in 268 Cases with Gram-negative Bacillary Pneumonia / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To study the pathogen distribution and drug-resistance status of Gram-negative bacillary pneumonia and draft preventive and control measures.METHODS The sputum and lower respiratory tract secretion of 268 patients with Gram-negative bacillary pneumonia were cultured to detect pathogens.Susceptibility test was performed.Then the results were analyzed retrospectively.RESULTS Detection rates of Pseudomonas aeruginosa rated the top one,reaching 29.9%;then was Klebsiella pneumoniae,accounted for 19.4%;Acinetobacter baumannii ranked the third,accounted for 15.3%.The drug-resistance supervision manifested that the resistant rate of Gram-negative bacteria to ampicillin was the highest,reached 81.6-94.7%;that to imipenem was the lowest,reached 0-2.5%.And extensive-spectrum beta-lactamases(ESBLs) occurred with 30.0%.CONCLUSIONS The higher drug-resistance to common antibiotics occurs in Gram-negative bacillary pneumonia in our hospital.Clinical microbiology department should monitor pathogens well to provide the evidence for infection controlling.