Long-term Follow-up of an Evans Syndrome with Chronic, Refractory Course: Response to 5 Different Regimens / 대한소아혈액종양학회지
Korean Journal of Pediatric Hematology-Oncology
;
: 234-238, 2002.
Article
in Korean
| WPRIM
| ID: wpr-59292
ABSTRACT
Evans syndrome is the combination of direct Coombs' positive hemolytic anemia and immune thrombocytopenic purpura, in the absence of a known underlying etiology. Being reported rarely in pediatric patients, the syndrome is characterized by periods of remission and exacerbation with viable responses to therapy. Management of the disease remains a challenge despite a variety of therapeutic trials. We experienced a 11-years old male patient of Evans syndrome who was initially presented as having an autoimmune hemolytic anemia 17 months before. Over the 5 years of follow-up, he had a chronic, relapsing courses, showing partial responses to a variety of therapeutic trials, including IVIG, oral prednisolone, methylprednisolone pulse therapy, cyclosporine A and vincristine. A brief review of the literature ensues with the case report.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Vincristine
/
Methylprednisolone
/
Prednisolone
/
Follow-Up Studies
/
Purpura, Thrombocytopenic, Idiopathic
/
Immunoglobulins, Intravenous
/
Cyclosporine
/
Anemia, Hemolytic
/
Anemia, Hemolytic, Autoimmune
Type of study:
Observational study
/
Prognostic study
Limits:
Child
/
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Pediatric Hematology-Oncology
Year:
2002
Type:
Article
Similar
MEDLINE
...
LILACS
LIS