Efficacy of Glycopyrrolate in Primary Hyperhidrosis Patients
The Korean Journal of Pain
;
: 28-32, 2012.
Article
in English
| WPRIM
| ID: wpr-59302
ABSTRACT
BACKGROUND:
Primary hyperhidrosis is a disorder of excessive sweating, which shares several features with anxiety disorders and has a negative impact on a patient's quality of life. Oral glycopyrrolate is one of the treatments available. There are a few published studies on the use of glycopyrrolate given orally in the treatment of hyperhidrosis.METHODS:
Thies is study was a review of case notes in a series of 36 patients with primary hyperhidrosis. We made a comparison between the Keller's scale score of a pre-glycopyrrolate medication group and the Keller's scale score f a post-glycopyrrolate medication group. The Milanez de Campos score, Short Form_36 (SF-36) score, Beck Depression Inventory (BDI) score, Beck Anxiety Inventory (BAI) score, and autonomic nervous system (ANS) scale score were also compared between the two groups.RESULTS:
In the post-glycopyrrolate medication group, there were declines in Keller's scale, and Milanez de Campos scale score and BAI score (P < 0.001). In addition, there were increases in SF_36 score in the post-glycopyrrolate medication group (P = 0.03) However, no changes were seen in, BDI score and ANS score in the post-glycopyrrolate medication group (P < 0.001).CONCLUSIONS:
Glycopyrrolate is an effective initial method of treating primary hyperhidrosis that, reduces anxiety and improve patients' quality of life.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Anxiety
/
Anxiety Disorders
/
Quality of Life
/
Autonomic Nervous System
/
Sweat
/
Sweating
/
Cholinergic Antagonists
/
Depression
/
Glycopyrrolate
/
Hyperhidrosis
Limits:
Humans
Language:
English
Journal:
The Korean Journal of Pain
Year:
2012
Type:
Article
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