Morphological Changes of Neurons in the Dorsal Horn Resulted from Different Types of Spinal Cord Injury / 昆明医科大学学报

ABSTRACT

To explore the characteristic features of morpho logical changes of neurons in the spinal dorsal horn result from different types of spinal cord in jury, the adult Srague-Daweley fat models of crushed, hemi-sected and transected spinal cord injury established in our laboratory were used, and the intact spin al cords were as control． 　　These rats were sacrificed after 24 hours, 7 days and 2l days of operation, and the L3, segments were removed out and sectioned continuously into sections of 20 μm in thickness． The sections were stained by hematoxylin and observed under ． 　　 microscope． In addition, neurons in the dorsal horn were counted． 　　 Results: In the crushed spinal horns, bodies of neurons were atrophy, but neuron counting did not decrease markedly; in the hemi-sected and transected dorsal horn, a batch of empty cavities were presented, and neuron counting decreased greatly． The results indicated that different injuries of spinal cord resulted in different damage to neurons in the dorsal horn, i． e． the crushed one, the bad, the hemi-sected one, the worse; and the transected one, the worst．