Influence of Endoscopic and Open Thyroidectomies on Immune Function / 中国微创外科杂志

ABSTRACT

Objective To compare the influence of endoscopic thyroidectomy via breast areola approach and traditional thyroidectomy on the immune function.Methods Fifty cases undergoing partial thyroidectomy were divided into endoscopy and open thyroidectomy groups(25 cases in each).Blood samples were obtained at 1 day before the surgery and 1,2,and 3 days postoperation to count the CD3,CD+4 and CD+8 T lymphocytes using flow cytometry,and determine the concentration of immunoglobulins(IgG,IgA,and IgM),CRP,and complements(C3 and C4)with immunonephelometry.Results In both the groups,the concentrations of CD3,CD+8 T lymphocytes,and complement C4 decreased significantly at 24 hours after the surgery(P0.05).Conclusions Both endoscopic and traditional thyroidectomy could depress the immune function,however no significant difference exists between the two methods in the level of depression.