Cloning of the novel putative apoptosis-related gene of Spirometra erinacei (Order Pseudophyllidae)
The Korean Journal of Parasitology
;
: 233-237, 2006.
Article
in English
| WPRIM
| ID: wpr-59375
ABSTRACT
We postulated that apolysis was processed in accordance with apoptotic changes occurring in a cestode, Spirometra erinacei (Pseudophyllidea). We cloned the novel putative apoptosis-associated gene from S. erinacei via screening of a S. erinacei cDNA library with a ced-3 gene (activator of apoptosis) probe from Caenorhabditis elegans. We identified a 261-bp cDNA sequence, which encodes for an 86-amino acid protein. The cloned gene expression was observed in the neck and gravid proglottids via Northern blotting, using cloned cDNA inserts as probes, but the clone was not expressed in any of other tissues. We suggest that this gene may be involved in the apolysis of S. erinacei during normal tissue development and differentiation in cestode parasites.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Spirometra
/
Molecular Sequence Data
/
Base Sequence
/
Gene Library
/
Amino Acid Sequence
/
Cloning, Molecular
/
Apoptosis
/
Caspases
/
Caenorhabditis elegans Proteins
Limits:
Animals
Language:
English
Journal:
The Korean Journal of Parasitology
Year:
2006
Type:
Article
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