Bacterial Distribution and Antimicrobial Resistance in a General Hospital / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To investigate the distribution and resistance of commonly encountered pathogens in a General Hospital,and provide reference for antimicrobial agents usage.METHODS All pathogenic bacteria were isolated from the clinical specimens during the last four years and samples were identified.K-B method was performed to test the antibiotic resistance.RESULTS Among 1643 isolates,The Gram-negative bacteria Pseudomonas aeruginosaand Escherichia coli,and the Gram-positive bacteria Staphyococcus epidermidisand S.aureus were the main pathogens.The P.aeruginosa was highly resistant to broad-spectrum penicillins,third-generation cephalosprins,aminoglycosides and quinolones.But impenem showed activity against Gram-negative bacilli,with resistant rates less than