Pathogen Distribution and Drug Resistance in Venous Catheterization Infection / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To investigate antibiotic resistance and distribution of bacteria to provide reference for using antibiotics reasonably.METHODS Antibiotic susceptibility test was performed by K-B method,meticillin-resistant Staphylococcus(MRS)and ESBLs were identified according to NCCLS(2004)of the USA.RESULTS From in 118 strains of bacteria there were 75 Staphylococcus strains,and the isolated rate of meticillin-resistant S.aureus(MRSA)was 35.0%,and that of meticillin-resistant coagulase-negative S.aureus(MRCNS)was 40.0%.Among 41 Gram-negative bacilli,ESBLs isolating rates in Escherichia coli and Klebsiella pneumoniae were 18.2% and 30.0%,respectively.The resistant rate to clindamycin,erythromycin and ciprofloxacin in MRS was higher than in meticillin-sensitive Staphylococcus(MSS)significantly.Imipenem showed proper antibiotic activity to Gram-negative bacilli.CONCLUSIONS We should pay more attention to resistant strains to control the nosocomial infection outbreaking.