Telomere length and chronic compartment syndrome in the lumbosacral region / 中国组织工程研究
Chinese Journal of Tissue Engineering Research
;
(53)2007.
Article
in Chinese
| WPRIM
| ID: wpr-593850
ABSTRACT
BACKGROUND:
There is a close correlation between telomere length and cell senescence, immortalization or canceration.OBJECTIVE:
To explore the significance of telomere length diversifies in the chronic compartment syndrome in lumbosacral region. DESIGN, TIME ANDSETTING:
A comparative observation was performed at the State-Level Key Medical Genomics Laboratory, Shanghai Jiao Tong University School of Medicine from July 2007 to February 2008.PARTICIPANTS:
The vertical spinal muscular tissue samples were taken from people aged 29-49 years old [mean aged (34.7?12.6) years] including 10 normal people and 15 patients with chronic compartment syndrome. According to the age, the normal were divided into the aged 30-37, and aged 38-45 groups. The abnormal were divided into aged 29-34, aged 35-43 and aged 44-49 groups, with 5 samples in each group.METHODS:
DNA was extracted from samples of each group. Telomere length in vertical organizations spinal muscular skeletal muscle was measured by Southen Blotting hybrid technology. MAIN OUTCOMEMEASURES:
Telomerase length of erector spinal muscles in patients and normal people.RESULTS:
The mean telomere length in patients with chronic compartment syndrome was obvious shorter than that of the normal people, which has significant difference (P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Tissue Engineering Research
Year:
2007
Type:
Article
Similar
MEDLINE
...
LILACS
LIS