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Therapeutic effect of growth hormone, glutamine and optimal diet for patients with short bowel syndrome / 医学研究生学报
Journal of Medical Postgraduates ; (12)2004.
Article in Chinese | WPRIM | ID: wpr-593935
ABSTRACT

Objective:

To determine if growth hormone (GH) and glutamine (Gln) reduce the time and dose of parenteral nutrition (PN) in patients with short bowel syndrome.

Methods:

Sixteen PN-dependent patients with short bowel syndrome were randomly assigned to Group A (control, oral Gln [0.6 g/kg/d] + GH placebo + diet, n= 5), B (Gln placebo + GH [8 IU/d] + diet, n= 5), and C (Gln + GH + diet, n= 6). PN volume and content were determined by standard criteria based on clinical measurements. After 4 weeks, GH and GH placebo were discontinued, but the diet with Gln or Gln placebo was continued for 12 weeks.

Results:

Group B showed greater reductions in PN volume, PN calorie and PN frequency than Group A (P

Full text: Available Index: WPRIM (Western Pacific) Type of study: Controlled clinical trial Language: Chinese Journal: Journal of Medical Postgraduates Year: 2004 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Controlled clinical trial Language: Chinese Journal: Journal of Medical Postgraduates Year: 2004 Type: Article