Changes of serum inflammatory mediators,lipid profile and left ventricular structure and their correlations in patients with essential hypertension / 医学研究生学报
Journal of Medical Postgraduates
; (12)2003.
Article
in Zh
| WPRIM
| ID: wpr-594466
Responsible library:
WPRO
ABSTRACT
Objective: Accumulating evidence shows that hypertension is a chronic low-grade inflammatory disease,and inflammatory reaction is involved in the formation and progress of target-organ damage in hypertension.The authors aimed to explore the changes in the serum levels of interleukin-6(IL-6),soluble CD40 ligand(sCD40L),metalloproteinase-9(MMP-9),tissue inhibitor of metalloproteinase-1(TIMP-1),lipid profile and left ventricular structure in patients with essential hypertension.Methods: The serum levels of IL-6,sCD40L,MMP-9 and TIMP-1,along with blood lipids were determined and echocardiography was performed to evaluate the cardiac structure and function of 158 hypertension patients and 22 age-and sex-matched controls.Results: The hypertension patients exhibited higher levels of IL-6(P
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Language:
Zh
Journal:
Journal of Medical Postgraduates
Year:
2003
Type:
Article