The virulence and the gene regulatory mechanism of SpA / 医学研究生学报

ABSTRACT

SpA,one of the important virulence factors of Staphylococcus aureus,can impede phagocytosis,induce apoptosis of B cells,initiate staphylococcal pneumonia and endocarditis,et al.The expression of Spa gene is regulated by a very subtle and complicated systematic web.With the mechanism of the virulence and the gene regulation of Spa were known more and more clearly,New methods of the infection by Staphylococcus aureus were would be found.