Successful Opening of Ductus Arteriosus with Milrinone in a Newborn with Tetralogy of Fallot and Pulmonary Atresia
Journal of the Korean Society of Neonatology
;
: 365-369, 2011.
Article
in English
| WPRIM
| ID: wpr-59455
ABSTRACT
Tetralogy of Fallot (TOF) assumes its' most severe form when accompanied by pulmonary atresia (PA). Preserving the patent ductus arteriosus to maintain pulmonary blood flow is life-saving for patients with this congenital heart disease. Milrinone, a selective phosphodiesterase III inhibitor, is a potent vasodilator. Here, we report the successful use of milrinone for a newborn infant with TOF and PA for keeping the ductus arteriosus open and thereby maintaining pulmonary circulation. Milrinone is a useful drug because of its inotropic, lusitropic, and pulmonary vasodilating effects, in addition to its ability to keep the ductus arteriosus open and its relatively mild side-effects. Case series and comparative studies will be needed in the future to verify the effectiveness of this drug.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Tetralogy of Fallot
/
Pulmonary Circulation
/
Pulmonary Atresia
/
Milrinone
/
Ductus Arteriosus
/
Ductus Arteriosus, Patent
/
Cyclic Nucleotide Phosphodiesterases, Type 3
/
Heart Diseases
Limits:
Humans
/
Infant, Newborn
Language:
English
Journal:
Journal of the Korean Society of Neonatology
Year:
2011
Type:
Article
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