Aminoglycoside-modifying Enzyme and 16S rRNA Methylase Gene Expressions in Acinetobacter baumannii / 中华医院感染学杂志
Chinese Journal of Nosocomiology
;
(24)2009.
Article
in Chinese
| WPRIM
| ID: wpr-596147
ABSTRACT
OBJECTIVE To understand aminoglycoside-modifying enzyme and 16S rRNA methylase gene expressions in Acinetobacter baumannii in Xinjiang region.METHODS 20 A.baumannii strains were isolated and test the anti-bacterial drug sensitivity.PCR methods were used to test aminoglycoside-modifying enzyme and 16S rRNA methylase gene.RESULTS From thirteen A.baumannii strains detected the aminoglycoside-modifying enzyme genes,the detection rate was 65%;in which aac(3)-Ⅰ gene was positive in 4 strains(20%),aac(3)-Ⅱ gene in 8 strains(40%),aac(6′)-Ⅰad gene in 4 strain(20%),ant(3″)-Ⅰ gene in 4 strain(20%),and ant(2″)-Ⅰ gene was positive in 1 strain(5%).The aac(6′)-Ⅰ b and aac(6′)-Ⅱ gens and were not detected;the 16S rRNA gene methylation was negative.CONCLUSIONS There are aminoglycoside-modifying enzyme genes existing in A.baumannii,no 16S rRNA methylase gene was detected in Xinjiang region.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Nosocomiology
Year:
2009
Type:
Article
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