MRI-guided Percutaneous Cryoablation for Hepatic Carcinoma:Report of 27 Cases / 中国微创外科杂志

ABSTRACT

Objective To study the feasibility,efficacy,and safety of MRI-guided percutaneous cryoablation for the treatment of hepatic carcinoma. Methods From January to September 2008,27 cases of hepatic carcinoma were treated with MRI-guided percutaneous cryoablation with Cryo-Hit system via two cycles of freezing-thawing. During the procedure,MRI showed the expansion of ice globe wrapping the tumor. Ten days after the freezing treatment,TACE was carried out in 5 cases. Results MRI-guided percutaneous cryotherapy were completed successfully in all of the cases. In 26 patients (96.3%),expanded ice globe wrapping the tumor was detected by MRI,showing a dark zone with clear margin. Only in one patient,the tumor was wrapped. The patients were followed up for 1 to 12 months (mean,3.5 months),during which the level of AFP decreased to a normal value in 14 cases (51.9%),continued to increase in 1 cases,and increased after an reduction in 12 cases (44.4%). The patients received more than one times of re-examination by imaging,which showed completed necrotic tumor tissues or no confirmed living tumors in 14 cases (51.9%); and incomplete tumor necrosis or living tumor lesions in 13 (48.1%). No severe complications occurred in this series.Conclusions MRI-guided percutaneous cryoablation is feasible,effecitve and safety for hepatic carcinoma.