VITEK32 Expert System for Detection and Analysis of Resistance Phenotypes in Commonly Encountered Bacteria:A Clinical Evaluation / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To evaluate VITEK32 expert system(7.02) for detection and analysis of clinically important resistance phenotypes.METHODS A total of 508 known resistant phenotype clinial strains and 9 standards strains were tested by VITEK32 expert system(7.02) and antibiotic susceptibilities were determined by CLSI recommendation.RESULTS The correct phenotype was identified by the expert system in one or more choices for 312 from the 508(61.4%) isolates and standards.The resistant phenotypes for meticillin-susceptible,and resistant Staphylococcus spp,extended-spectrum ?-lactamases(ESBLs) producingEscherichia coli,Klebsiella spp,AmpC producing Enterobacter,cloacae,Serratia marcescens,and vancomycin-resistant Enterococcus faecalis were accurately identified by VITEK32 expert system,this expert system was not including ESBLs producing Proteus mirabilis.CONCLUSIONS VITEK32 expert system can be accurately identified most clinically important bacteria based on phenotype.The data of ESBLs Producing P.mirabilis should be included in the further work on expert system.