Comparative study of PTN,Cyfra21-l and CEA test in diagnosis of lung cancer / 医学研究生学报

ABSTRACT

Objective: Serum pleiotrophin(PTN) is closely related to tumor,particularly to lung cancer.Many studies focused on PTN recently.This study is to evaluate the diagnostic value of PTN,Cyfra21-l and CEA tests independently or in a combined style in lung cancer.Methods: Sixty-one patients with lung cancer and 17 patients with benign lung lesion disease all received PTN,Cyfra21-l and CEA tests before the treatment.They were compared with pathological results,and then we calculated the diagnostic value of each method and the combined styles.Results: The sensitivity of PTN together with Cyfra21-l and CEA tests is 95.08% and it is the highest among the methods.Conclusion: PTN together with Cyfra21-l and CEA tests has a important diagnostic value through mutual complementation in detecting lung cancer.