Where are We Now with Decompressive Hemicraniectomy for Malignant Middle Cerebral Artery Infarction?
Journal of Cerebrovascular and Endovascular Neurosurgery
;
: 61-66, 2013.
Article
in English
| WPRIM
| ID: wpr-59670
ABSTRACT
In spite of the best medical treatment, large hemispheric infarction, resulting from acute occlusion of either the internal carotid or the proximal middle cerebral artery with insufficient collateral blood flow is associated with a high case fatality rate of approximately 60%. Thus, a decompressive hemicraniectomy is considered a life-saving procedure for this devastating disease. Findings of three recent randomized, controlled clinical trials and their meta-analysis showed that early surgical decompression not only reduced the number of case fatalities but also increased the incidence of favorable outcomes. The authors review the pathophysiology, historical background in previous studies, operative timing, surgical technique and clinical outcomes of surgical decompression for malignant hemispheric infarction.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Brain Edema
/
Cerebral Infarction
/
Incidence
/
Decompression, Surgical
/
Middle Cerebral Artery
/
Infarction
Type of study:
Controlled clinical trial
/
Incidence study
/
Prognostic study
Language:
English
Journal:
Journal of Cerebrovascular and Endovascular Neurosurgery
Year:
2013
Type:
Article
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