Distribution and Drug Resistance of Pseudomonas aeruginosa in ICU / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To approach the distribution and drug resistance of Pseudomonas aeruginosa(PAE) in nosocomial infection in intensive care unit(ICU) and provide the evidence for clinical controlling of it.METHODS Clinical data of nosocomial infection with PAE isolated from ICU from Jan 2005 to Dec 2008 were investigated retrospectively.The results of susceptibility test in 277 PAE strains were analyzed statistically.RESULTS PAE strains were mostly isolated from respiratory tract(56.0%).The drug resistance rates to ceftriaxone,cefotaxime and gentamicin were all above 64.0%.PAE was resistant to the other antibiotics in different degrees.The suceptibility rates to imipenem,meropenem,amikacin,cefoperazone/sulbactam,piperacillin/tazobactam and levofloxacin were all above 74.0%.CONCLUSIONS The clinician should use the antibiotics reasonably according to etiological testing to elevate the level of anti-infection treatment.