Iron metabolism and neonatal hypoxic-ischemic encephalopathy / 国际儿科学杂志

ABSTRACT

Iron homeostasis is essential for the maintenance of the body. Iron transports oxygen and electron, and participates in the synthesis of neurotransmitters and myelin. However, iron overload in the body is harmful. In recent years studies have found iron deposition would be poisoned significantly, particularly in the central nervous system tissues and nerve cells, which will cause pathological changes of central nervous system.This paper describes the iron and cycled iron changes in hypoxic-ischemic brain, abnormal iron metabolism and mechanisms of HIE.